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To understand ARA-290, we have to look at a hormone you might already know: Erythropoietin, or EPO

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This structural modification improves bioavailability in research models but also makes the molecule more susceptible to denaturation under improper storage conditions than endogenous IGF-1

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This confirmed that mTORC1 activation is the primary route through which glycine preserves muscle mass

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PMCID: PMC6393210.

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