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Treatment of mice with 2APB 2APB (Sigma, D9754) was made fresh for each experiment (dissolved in DMSO at 100 mg/ml as the stock)

Adverse events were similar between groups, including hypoglycemia, which affected none of the patients in the placebo arm and one patient in the sitagliptin arm

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Sekeres MA, Schoonen WM, Kantarjian H, et al

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