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Training requirements Progressive overload essential: Gradually increase weight, reps, or volume Peptides support this but don't replace it Track all workouts Optimal frequency with peptides: Can train each muscle 2-3x weekly (enhanced recovery) Higher volume tolerated Shorter rest periods needed Periodization: Strength phases (3-6 reps) Hypertrophy phases (8-12 reps) Deload weeks still important Peptides amplify training stimulus - still need stimulus

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For patients already engaged in a comprehensive longevity program that includes metabolic monitoring, MOTS-c fits naturally into the toolkit