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doi: 10.1016/j.molcel.2008.04.012

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These next-generation agents engage not only GLP-1 receptors but also those for other gastro-entero-pancreatic hormones such as glucose-dependent insulinotropic polypeptide (GIP), glucagon, amylin, and peptide YY to enhance energy uptake, storage, and expenditure through synergistic mechanisms

The peptide upregulates expression of epidermal growth factor, hepatocyte growth factor, and vascular endothelial growth factor among others