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This dual mechanism makes it more effective than single-target medications like semaglutide for some patients

Label transfer of primary hypothalamic neurons onto hPSC-derived neurons was performed by finding the 10 nearest primary hypothalamic neurons neighbours for each hPSC-derived neurons using the queryKNN function from the BiocNeighbors R package on the integrated space, followed by assigning the most common primary hypothalamic neuron cell type from the neighbouring cells