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While topical application has minimal systemic absorption, the precautionary principle suggests avoiding use during pregnancy unless a healthcare provider approves

[1] [13] However, serum B12 has limitationslevels between 148258 pmol/L represent a 'grey area' where deficiency may still be present, particularly if clinical features are suggestive

Too Much B12 and Acne You may have heard that vitamin B12 can cause acne, but that isnt the whole story