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Nature 487, 443448

351 In the process of ferroptosis, cells are affected by oxidative stress and lipid peroxidation, resulting in the rupture of cell membranes and cell death, which is manifested mainly by the reduction in GPX4, the core enzyme of the antioxidant system (glutathione system), and the high expression of the lipid peroxidation marker 4-HNE

It may not completely cure or prevent any symptom, illness or disease on its own

The oxidative stress caused by dying rods then causes degeneration of the cones, which at only 2% of the photoreceptors in the mouse retina, become overwhelmed by the oxidative damage [44, 45]