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A 2025 study in JAMA Network Open found that people with type 2 diabetes who took semaglutide (Ozempic) or tirzepatide (Mounjaro) had a 76% higher risk of developing a rare condition called nonarteritic anterior ischemic optic neuropathy (NAION)

The fact that calcium removal is proportional to calcium concentration enables exponential decay in calcium levels, as was also experimentally observed (Itskovits et al , 2018)