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Common Side Effects Mild injection site reactions Transient water retention Mild joint stiffness Less Common Considerations Elevated IGF-1 beyond target range Glucose dysregulation in poorly selected patients Tesamorelin should be avoided in patients with active malignancy , as growth hormone can promote cellular proliferation

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In this study, B12 levels were 244 pmol/l or more in all patients at baseline, but in those who improved, B12 levels almost quadrupled, whilst in non-responders B12 levels went up by only 50%