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Immunopharmacol 6, 587592
In animal studies, AOD-9604 reduced body weight gain by over 50% in obese mice during a 19-day treatment period, and significantly increased fat oxidation all without affecting insulin sensitivity or glucose regulation.[1,3] A randomized controlled trial in humans found that participants taking 1 mg of AOD-9604 daily lost an average of 2.8 kg (~6 lbs) over 23 weeks, compared to 0.8 kg (~1.7 lbs) in the placebo group
Because traditional centrifugation-based methods are too slow to preserve ER metabolite content, we adapted an immunopurification strategy previously developed for other organelles 1315
2003 Apr;384(4):505-16
Supporting the bodys natural GLP-1 activity, particularly through dietary and microbiome-related interventions, offers a gentler and potentially more sustainable approach
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