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OX40 agonist combined with irreversible electroporation synergistically eradicates established tumors and drives systemic antitumor immune response in a syngeneic pancreatic cancer model

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Rats with acute pancreatitis had a 21% reduction in cardiac output, a 37% decrease in contractility, a 23% decline in diastolic tension, and a twofold increase in the cardiac tissue edema index [80]