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Description

The binding properties of the expressed receptor are similar to native receptors

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A proportion of those with an imprinting defect have a microdeletion in the Imprinting Center

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This dose results in exposures approximately 60 times the human exposure at the maximum recommended daily adult human dose (MRHD) of 100 mg/day based on AUC comparisons

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Nat Rev Endocrinol (2011) 7(9):5056

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