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Early data from amycretin showed up to 13.1% weight loss in just 36 weeks of a phase 1/2 trial, with the weight loss curve still descending steeply

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Kaempferol activates the Nrf2/SLC7A11/GPX4 pathway, boosting antioxidant defenses and reducing neuronal ferroptosis in OGD/R-induced damage, showing promise for CIRI treatment, though further animal studies are needed (Yuan et al., 2021)

1: Sikiric P, Barisic I, Udovicic M, Lovric Bencic M, Balenovic D, Strinic D, Posilovic GZ, Uzun S, Vranes H, Krezic I, Lozic M, Stambolija V, Premuzic Mestrovic I, Oreskovic LB, Kalogjera L, Strbe S, Sikiric S, Tomic L, Stupnisek M, Kordic M, Tvrdeic A, Seiwerth S, Boban Blagaic A, Skrtic A

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