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There is baseline secretion of GLP-1 even during fasting (510 pm), but postprandially induced production increases with meal size (1030 pm)

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Effects of GLP-1RA in the General Population The effects of GLP-1RA on mortality and weight loss outcomes have been studied in a variety of higher-risk populations, including subjects with obesity, higher cardiovascular risk, type 2 diabetes mellitus, and metabolic dysfunction-associated steatohepatitis (Table 1)

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