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These can include: Nausea and stomach discomfort A common early side effect that is often temporary
They slow gastric emptying, help the body respond better to insulin, and reduce food intake by improving satiety and curbing cravings
Also, pericytes in the BBB differ from pericytes in the body in their numbers, that is, there is a large number of pericytes located in the CNS compared to other body tissues, thereby making the ratio of pericytes to endothelial cells in the CNS higher (1:1 to 1:3) compared to other cells, such as the muscles (1:100)
Changes in sleep architecture from the metabolic transition may alter the balance between REM (dream) sleep and non-REM deep sleep
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Gut Microbiome Impact: Gut integrity is essential for immune function
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