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ACHIEVE-3: Oral GLP-1 add-on therapy for diabetes management in adults with T2D on metformin, once-daily oral #orforglipron was superior to 14 mg oral #semaglutide (Rybelsus version) for 52-week HbA1c lowering, with greater weight loss but more GI AEs and higher heart rate increase

(2025) The multifaceted effects of Semaglutide: broad therapeutic applications

It may also influence blood glucose levels, thyroid function, and immune responses, which could theoretically have implications for patients taking medications like Wegovy

It means theres weight dependent and weight independent effects on the heart, she added

Prevounce recommends that you consult with your payers, reimbursement specialists, and/or legal counsel regarding coding, coverage, and reimbursement matters