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However, those drugs are only FDA-approved to treat type 2 diabetes (along with diet and exercise), not obesity

The result at week 68: Continued semaglutide 2.4 mg: lost an additional 7.9% of body weight (total loss from baseline: 17.4%) Switched to placebo: regained 6.9% of body weight (net loss from baseline: 5.0%) Thats a roughly 15-point difference in body weight between the two groups at the end of the trial, attributable entirely to whether the medication continued

Both drugs are administered via subcutaneous injection, but they differ in their duration of action

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P-methyl-BHA (MBHA) resin was purchased from Applied Biosystems, Boc protected amino acids were purchased from Peptides Institute