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Both these neuron systems express estrogen receptors: ER is predominantly expressed in the POMC (proopiomelanocortin) neurons, while both ER and ER are present in neuropeptide Y (NPY) and agouti-related protein peptide (AgRP) neurons (78, 79)

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HOWEVER getting over a certain amount of calcium from supplements was associated with 20% higher risk of men dying from cardiovascular disease