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Hepatology 44(4):788794

PMID: 36825700 Xu H, Zhang C, Qian Y, Zou J, Li X, Liu Y, Zhu H, Meng L, Liu S, Zhang W, Yi H, Guan J, Chen Z, Yin S (2020) Efficacy of melatonin for sleep disturbance in middle-aged primary insomnia: a double-blind, randomised clinical trial

To determine whether the pharmacotherapy-induced reduction in muscle mass is maladaptive (i.e., impairs muscle function) or adaptive to lower body weight with minimal functional consequence, objective functional testing is required to assess muscle strength and physical functional performance

Our goal is to help you understand your choices and make informed decisions whether about the medication itself, the dose, or how you take it

Adjusted odds ratios (OR), for age, sex, body mass index, and diabetes, were pooled