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It works by stimulating insulin production in the pancreas and decreasing glucagon production, which helps to reduce blood glucose levels in the blood

The oncometabolite D-2HG produced in IDH-mutant tumors from KG contributes to inhibiting antitumor immunity via the metabolic reprogramming of CD8+ T cells and decreasing their proliferation and antitumor toxicity [100]

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Frondoside A downregulates Bcl-2 and survivin, increases ROS production, and promotes cytochrome c release, ultimately triggering mitochondrial apoptosis c release, ultimately triggering mitochondrial apoptosis (127)

insulin glargine in type 2 diabetes: cost-effectiveness analysis in the German setting