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For doses exceeding 1.0 mL, either split into multiple injections at different sites or use multiple vials as needed

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Ardoin, S

However, it is worth noting that: The medication is relatively new, with limited long-term data beyond three years Colorectal cancer typically develops over many years, making short-term trial data insufficient to rule out very rare long-term risks Ongoing real-world studies and registry data will provide more comprehensive safety information as the medication is used in broader populations Patients should be reassured that current evidence does not support a direct link, but continued monitoring and research remain essential components of responsible prescribing and pharmacovigilance