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Interestingly, semaglutide treatment did not alter the ratio of phosphorylated versus total Akt in LPD mice, thus invalidating our hypothesis of semaglutide-induced IGF-1 resistance in the muscle of these animals

The drug was working to treat diabetes by slowly releasing insulin from the pancreas, but they had also stumbled upon an interesting side effect the drug made people not want to eat

Neither switch is something to attempt without guidance, since dosing schedules differ between the two medications and starting at the wrong dose can increase side effects unnecessarily