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Many users have reported digestive issues while taking the medications, including nausea, vomiting, constipation and diarrhea, along with headaches, fatigue and changes to the skin

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WHAT TO EXPECT Treatment starts at a low dose and escalates gradually over 16 weeks to minimise gastrointestinal effects

Secondary outcomes include change in waist circumference, change in BMI, change in percent body fat, change in visceral and subcutaneous adipose tissue, change in trunk fat mass, percentage of weight loss due to fat mass or lean mass, quality of life, and more

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