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[1] Citrulline supplements without the malic acid (AKA L-citrulline) may have some similar benefits, however, the impact on energy production likely isn't as profound

As we age, the size of the thymus decreases, which some have suggested could be the root cause of age-related decreases to immune function, resulting in higher incidences of infections and autoimmune diseases

Some additional benefits of liver support include a reduction of fatigue, brain fog, anxiety, and depression, as well as clearer skin, improved vitamin and mineral absorption, and better bowel function

For patients with chronic migraines, any headache after the treatment is usually part of their condition, not caused by the injections

however, direct human evidence for these mechanisms remains limited