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Most patients regain weight after stopping GLP-1 medications, with clinical trials showing approximately two-thirds of lost weight returns within one year

For most patients, the glycaemic and weight loss benefits of tirzepatide may outweigh the risk of headaches, which are typically manageable and often transient

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Other GLP-1 based drugs, such as the DPP-IV inhibitors sitagliptin and linagliptin, are also available for the treatment of type II diabetes

In India, where out-of-pocket healthcare spending is high, the cost of branded weight-loss injections has remained a significant barrier for many who need them