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The Gila monster's unlikely legacy The class of drugs that Ozempic belongs to generated $21 billion in sales in 2023 alone

GLP-1 agonists seem to do more than control blood sugar they may also protect your kidneys and heart

Therefore, intrinsic cardiac load and capacity do not improve in patients with heart failure with reduced ejection fraction, and patients HFpEF benefit only from the treatment of abnormal metabolism and inflammation.475,480,481 The encouraging results obtained with semaglutide in patients with heart failure and a preserved ejection fraction may provide a new option for this patient population, in which additional therapy, as well as another upstream therapy for patients with a higher BMI who have indications for this condition, is urgently needed

For functional enrichment analysis, enriched gene sets were determined by applying the same workflow used for RNA, using the R package gprofiler2 (v.0.2.0)