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1 Risk factors include female sex, older age, higher numbers of drugs, immunocompromised status, and autoimmune disorders

In AD, A damages microglia, produces inflammatory cytokines and chemokines, and affects surrounding CNS resident cells (astrocytes, oligodendrocytes, and neurons), which may aggravate tau pathology and ultimately lead to neurodegeneration and neuron loss.166 Inflammation may also be a potential link between diabetes and AD

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