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This means your trough level (the lowest point before your next injection) is significantly higher than it was during your first few weeks of treatment

It is added because it addresses two specific and significant clinical problems that arise from GLP-1 receptor agonist therapy: nausea at treatment initiation and progressive B12 depletion over the course of long-term use

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When to Investigate Further: Identifying Underlying Causes and Supportive Measures When diarrhea is severe, consider checking for bile acid malabsorption or pancreatic insufficiency if stools are fatty or greasy

Iron is another concern, especially for menstruating women