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SS-31s effects on muscle tissue make it particularly relevant for active patients and athletes: Improved lactate clearance: mitochondrial efficiency affects how quickly lactate accumulates during high-intensity exercise and how quickly it is cleared during recovery Reduced exercise-induced oxidative stress: the oxidative stress generated by intense exercise is substantially mitochondrial in origin

The inhibitory output interferes with the movement-related center in the thalamus and generates hypokinetic PD symptoms [73]