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However, excessive NO, often produced by inducible nitric oxide synthase (iNOS), amplifies Th2-driven responses, contributing to airway hyperresponsiveness and tissue damage in allergic inflammation [49]

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It is possible that such minor gene effects may be additive and particular combinations of polymorphisms from different genes may confer neuroprotection

Molecular analysis of the pathway for the synthesis of thiol tripeptides in the model legume Lotus japonicus

To verify if the increased expression of GCLC , GSS , and GSR had a functional impact on the activity of the GSH pathway, we measured total intracellular glutathione levels and ratio of reduced (GSH) to oxidized (GSSG) glutathione after 24 hours of BDG exposure ( Figure 4D )