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These are usually mild and temporary: Nausea , often mild and usually subsides after a few weeks Diarrhea or constipation , which can be lessened with small dietary changes Low appetite , which is usually the intended effect These side effects tend to diminish as your dose builds and your body grows accustomed to it
Notably, a dose-dependent increase in heart rate, peaking at 24 weeks, subsequently decreased [19]
If hunger is the main driver of weight regain, GLP-1/GIP strategies tend to be more directly matched to the problem