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The incidence of heartburn increases from about 8% at 5 mg to about 11% at 15 mg in clinical trials

Furthermore, there is no large force spike when the device is actuated, as there is with legacy spring-powered autoinjectors, and this soft start makes the delivery force curve very consistent

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Potential Challenges and Limitations Water recycling also requires careful planning and management

EEG recording and sleep induction Patient preparation and recording took place at the department's EEG laboratory in a quiet room with low-light levels