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Lipman, G

Acylcarnitines: potential implications for skeletal muscle insulin resistance

Clinical trials show that participants lost about 2% of body weight within the first four weeks when combined with dietary changes and regular physical activity

The emergence of GIPR/GLP-1R co-agonists has fostered a growing interest in the actions of GIP and glucagon-like peptide-1 (GLP-1) in metabolically relevant tissues, including liver, muscle and adipose tissue, regarding the control of glucose and lipid homeostasis

A: A GLP-1 agonist like semaglutide targets only the GLP-1 receptor, primarily suppressing appetite and slowing digestion