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To sum up, ROS can be directly involved in UV-induced apoptosis [51] by not only destroying several key structural and functional proteins and DNA but also inducing the release of cytochrome c (cyt-c) from the mitochondria, thereby accelerating photodamage of the skin [52]

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10.1073/pnas.0504978102 72

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M., Bowen W

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Ammonium accumulation disrupts NK cell metabolism by impairing glycolysis and OXPHOS, both of which are essential for ATP production and cytotoxic activity (142, 227)

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