Higher concentrations (20mg/ml) appear deeper blue than lower concentrations (5mg/ml)
The formula also contains deglycyrrhizinized licorice (DGL) and aloe vera, which have traditionally been used to promote digestive comfort and support healthy mucosal tissues
Andrographolide Andrographolide (AD) is the main active diterpenoid alkane separated from the leaf extract of Andrographis paniculata (Burm
Notably, animal models have demonstrated that transferring dysbiotic microbiota from CFS/ME patients to germ-free mice can induce fatigue-like behaviors, supporting a causal role for the microbiome in disease pathogenesis ( 3.5.4 Gut microbiota-based therapeutic interventions 3.5.4.1 Probiotics Given these findings, probiotic supplementation, particularly with strains of Lactobacillus and Bifidobacterium , has shown potential to restore microbial balance, enhance SCFA production, and reduce inflammation in CFS/ME patients (Carrasco-Querol et al., 2024
Nevertheless, there is a lack of the relevant cell lines to model the whole sophisticated cell interaction for both BBB and BCB, which is especially problematic for the latter since it is combined with a more model-challenging barrier geometry (Strazielle and Ghersi-Egea, 2011)