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2C ) and electric-field-driven motors [128, 129]

Consequently, T-MNS was administered to the CNV model via eye drops, and demonstrated outstanding safety and therapeutic effects

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In mammalian cells, ER stress leads to an integrated stress response involving the related transmembrane kinases Ire1, Ire1 and PKR-like ER kinase (PERK), and the transmembrane activating transcription factor 6 (ATF6) (Zhang & Kaufman, 2004)

We also wish to thank Michal Rjeck and Veronika Gajdukov for help with the preparation of figures, Sebastian Fica and Wojciech Galej for discussions and initial help, and Dr