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Evidence from non-metabolic chronic diseasessuch as inflammatory bowel disease, neurodegenerative disorders, and autoimmune conditionsremains sparse, restricting broader conclusions

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The regulation of melatonin, known for its effectiveness in enhancing cognitive function and preventing A accumulation, along with the involvement of the serotonergic system and histaminergic system in cognition and memory, becomes remarkable for promoting neurotransmission in AD