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In many countries tirzepatide has been overtaking semaglutide on the back of trial results suggesting marginally greater effectiveness

instead of 7 p.m.poses no significant clinical concern

This paradoxical effectopposite to diarrheamay result from excessive slowing of gut motility in certain patients or from dietary changes that accompany reduced appetite

CONCLUSIN Los datos del estudio SOUL muestran una mejora de la salud cardiovascular en los pacientes con DM tipo 2 y enfermedad cardiovascular/renal establecida (aunque solo el 13% de los pacientes incluidos tena enfermedad renal crnica) a expensas principalmente de la reduccin de los infartos no fatales, sin efecto en la mortalidad cardiovascular ni eventos renales