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To give yourself the injection, you'll place the pen on your stomach, thigh, or the back of your upper arm never in a muscle or near a vein and click the button on the top of the pen

For significant time zone changes (more than six hours), patients should consult their healthcare provider before travel to determine the optimal adjustment strategy

Additional reporting by Jonathan Stempel and Christy Santhoshediting by Caroline Humer, Nia Williams and Susan Fenton)

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