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High levels of chemokines can lead to the activation of the trigeminal nerve (an essential structure in migraine), the release of vasoactive peptides, and other biochemical mediators like nitric oxide

A key driver of neuronal injury is oxidative stress, which arises when the generation of reactive oxygen species (ROS) overwhelms the brains antioxidant defenses, one such defense being glutathione (GSH) (Dringen and Arend, 2025)

Connecting the Dots: from free radical lipid autoxidation to cell pathology and disease

Its crucial to understand what food to avoid when taking glutathione: Processed and Sugary Foods Exceptionally high processed foods or foods high in sugar make oxidative stress worse in your body

If they were persistent or severe, the parents were offered the option to discontinue the study