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The FDA said compounders will have 60 or 90 days to stop making copies of Novos drugs, depending on their type of facility

In the STEP 1 clinical trial, around 44% of people at the 2.4 mg dose reported feeling sick most often when they first started or moved up to a higher dose

Over 250 patients underwent metabolomics and lipidomic investigations, which revealed that unlike the baseline and placebo, tirzepatide, taken over 26 weeks, significantly impacted a group of lipids and metabolites like 3-hydroxybutyrate reduced branched-chain ketoacids (BCKA), branched-chain amino acids (BCAA), and direct catabolic products linked with obesity and insulin resistance

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