glutathione peroxidase 3 is a potential biomarker for konzo The glutathione peroxidase family: Discoveries

Antioxidants help reduce oxidative stress caused by free radicals, which can damage cells and contribute to visible signs of aging

The numbers tell the story: athletes receiving glutathione maintained muscle pH levels of 7.23 compared to 7.17 in control groups after hard exercise

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Cytosolic GSH increases because oxidative stress activates CBS and GCS increasing the flux through the GCS and GS reactions and simultaneously lowering the cytosolic cysteine concentration

MDM2 mediates the ubiquitin-dependent degradation of SPY1, resulting in a downregulation of SPY1 expression, which in turn upregulates the expression of ALOX15 and growth differentiation factor 15 (GDF15), while decreasing the levels of GCH1, GPX4, and GSH