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[PubMed: 6151126] 445

The peptide strengthens the intestinal barrier, reducing gut permeability and protecting against leaky gut

Anti-Doping Agency (USADA) Wada-Ama Patients asking about BPC157 can be given an evidence hierarchy summary: extensive animal data, limited early human pilot, zero large controlled efficacy trials and unknown long term safety

Human data: caution The only human data published to date are extremely limited: a 2024 pilot trial in 12 patients with interstitial cystitis treated with 10 mg of BPC-157 injected into the bladder wall, and a 2026 pharmacokinetic study in two healthy subjects (one 58-year-old man and one 68-year-old woman) receiving intravenous BPC-157