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1 The advantages of NOACs, also called direct oral anticoagulant drugs, include targeted mechanisms of action, predictability, few drug interactions, and the need for less frequent dosing and monitoring

Furthermore, nausea is among the most common side effects associated with GLP-1 receptor agonists in humans ( A limitation of the present study is the use of male rats, as sex-dependent differences have been reported across different stages of METH addiction in both humans and rodents (Yang et al., 2025), whereas preclinical studies have shown stronger suppression of alcohol self-administration and reinstatement in males, with females exhibiting less pronounced behavioral effects (Vallf et al., 2020)