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It is thought that the secondary pathway by which AOD9604 causes fat loss, the pathway that is independent of beta-3-adrenergic receptor activation, may play a role in improving metabolic metrics even while it boosts fat loss- AOD9604 exhibits minimal side effects, high oral and excellent subcutaneous bioavailability in mice
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doi: 10.1038/s41467-023-44412-7
And then there are surgical solutions, whichthough sometimes effectivecan be expensive, invasive, and offer mixed results
Shinotoh et al., 1993
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