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Advantages: Non-destructive measurement Rapid data acquisition Direct insight into folding behavior CD complements UVVis by revealing how binding affects overall peptide architecture

Development of an AAV-based gene therapy for the ocular phenotype of Friedreichs ataxia

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Another example of precursor use involves L-2-oxothiazofidine-4-carboxylate, which is converted to S-carboxyl-L-cysteine and undergoes spontaneous decarboxy-lation to liberate L-Cysteine, thereby supporting GSH synthesis

Daniel Goldenberg, Hadassah-Hebrew University Medical Center) and wild-type (WT) mice (FVB/N, ENVIGO), males and females, were maintained under specific pathogen-free conditions with a 12-h-light-dark cycle and permitted ad libitum consumption of water and standard chow