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While brain interstitial fluid tau concentrations are reported to be nearly twice as high during the active period of the rest-activity cycle in humans [8], it is noteworthy that, to the best of our knowledge, no study has investigated whether the deletion of core clock genes, simulating circadian disruption, leads to an increase in tau hyperphosphorylation

Nuclear factor erythroid 2-related factor 2 (Nrf2) functions as a transcription factor and a central regulator of the bodys oxidative stress response 11,12 , so that activating Nrf2 holds promise as an effective therapeutic strategy in OA

An open-lable, single-arm trial of the safety and efficacy of a novel preparation of glutathione as a skin-ligheting agent in Filipino women

Glutathione (GSH) is highly concentrated in the lung epithelial lining fluid (ELF) and protects against many inhaled oxidants