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The destruction of thyroid follicular cells in Hashimotos thyroiditis is mediated via T cells along with concurrent production of autoantibodies against thyroid-specific proteins including TPO and thyroglobulin

for instance, the upregulation of pyruvate carboxylation to generate oxaloacetate (OAA) has been observed in breast and pancreatic ductal adenocarcinomas (250)

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et al (2019) The Effect of Ingested Kerosene Contaminated Diets on the Liver, Kidney and Lungs of Wistar Albino Rats