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Self-diagnosing and self-treating with B12 shots (or high-dose tablets) without a confirmed deficiency is not advisable

Cost and accessibility : These drugs are relatively expensive and may be out of reach for low-income patients unless subsidized

Patients with partial or complete DPD deficiency are at high risk for severe, sometimes fatal toxicity when treated with fluoropyrimidines such as capecitabine

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454 Tissue repair significantly depends on injury-induced cellular dedifferentiation and plasticity