Geroprotective effect of epithalamine (pineal gland peptide preparation) in elderly subjects during accelerated aging
This dual action activates regenerative TGF- signaling while blocking fibrotic TGF-1/Smad2/3 pathways, demonstrating context-dependent regulatory sophistication
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Results: Significant improvements in skin hydration, elasticity, and smoothness, along with reductions in skin roughness, wrinkledness, and transepidermal water loss (TEWL).* Benefits were noticeable as early as 15 days and continued throughout the study, suggesting that WPLC (wheat polar lipids complex) is a promising supplement for enhancing skin health and combating aging-related skin concerns.* Wheat Lipid Supplementation for Dry & Aging Skin Study Randomized, double-blind, placebo-controlled, parallel study
Our data show that in our experimental periodontitis model ( i.e